Coronavirus

I’d say meet coronavirus but I think we’re all a bit too familiar at this point! ‬ ‪Coronaviruses are spherical, enveloped particles that vary between 80 and 120nm in diameter and carry an RNA genome (26.4 to 31.7kb). ‬ ‪The name “coronavirus” is derived from Latin – corona – meaning “crown”.‬ ‪The viral envelope isContinue reading “Coronavirus”

Adenovirus

Meet Adenovirus (not to be confused with adeno-associated virus from last post)!‬ ‪I have also worked pretty closely with Adenovirus in my scientific career. ‬ ‪Adenovirus (from the family parvoviridae) is 100nm in diameter, non-enveloped, and carries double-stranded DNA. The capsid is made of 720 protein subunits (known as hexons) arranged as an icosahedron. AtContinue reading “Adenovirus”

Adeno-Associated Virus

Meet Adeno-Associated Virus, also known as AAV!‬ ‪I have spent most of my scientific career working with AAV and have grown quite fond.‬ ‪AAV (part of the parvoviridae family) is a small (25nm in diameter), non-enveloped, virus carrying single-stranded DNA. The capsid is made of 60 protein subunits (known as VP1, VP2, and VP3) arrangedContinue reading “Adeno-Associated Virus”

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